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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R4
All Species:
12.42
Human Site:
S853
Identified Species:
27.33
UniProt:
Q6NUP7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUP7
NP_066009.2
873
99452
S853
G
N
S
V
D
P
K
S
S
G
S
K
D
T
Q
Chimpanzee
Pan troglodytes
XP_522937
1109
124026
S1089
G
N
S
V
D
P
K
S
S
G
S
K
D
T
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547959
916
103055
L888
S
F
P
S
N
P
S
L
P
S
T
S
R
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0Y0
875
99462
S855
G
N
T
A
D
P
K
S
S
G
S
K
D
A
Q
Rat
Rattus norvegicus
NP_001128104
821
93759
P799
P
A
N
F
S
P
N
P
V
L
P
S
T
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511225
842
94937
I821
P
L
P
G
T
S
Q
I
A
D
S
T
D
T
K
Chicken
Gallus gallus
XP_421339
873
99507
N853
F
N
S
A
D
Q
K
N
N
G
N
K
E
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696336
875
98944
S848
S
S
S
V
D
H
R
S
N
G
N
K
D
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393531
722
82259
E703
T
S
P
R
P
S
A
E
S
L
K
T
R
Y
I
Nematode Worm
Caenorhab. elegans
NP_495884
986
111167
N954
M
N
A
R
S
S
S
N
I
R
R
P
G
Y
G
Sea Urchin
Strong. purpuratus
XP_781974
792
88319
E773
S
P
S
A
T
L
L
E
P
N
N
N
V
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
N.A.
88.3
N.A.
90.7
83.8
N.A.
65.2
79.8
N.A.
59.2
N.A.
N.A.
31.2
23.2
40.8
Protein Similarity:
100
78
N.A.
90.5
N.A.
95
88.5
N.A.
78.4
91.1
N.A.
77.1
N.A.
N.A.
49.8
45.5
60.9
P-Site Identity:
100
100
N.A.
6.6
N.A.
80
6.6
N.A.
20
46.6
N.A.
60
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
20
N.A.
86.6
26.6
N.A.
40
80
N.A.
86.6
N.A.
N.A.
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
28
0
0
10
0
10
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
46
0
0
0
0
10
0
0
46
0
0
% D
% Glu:
0
0
0
0
0
0
0
19
0
0
0
0
10
0
0
% E
% Phe:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
28
0
0
10
0
0
0
0
0
46
0
0
10
10
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
37
0
0
0
10
46
0
10
10
% K
% Leu:
0
10
0
0
0
10
10
10
0
19
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
46
10
0
10
0
10
19
19
10
28
10
0
0
0
% N
% Pro:
19
10
28
0
10
46
0
10
19
0
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
46
% Q
% Arg:
0
0
0
19
0
0
10
0
0
10
10
0
19
0
10
% R
% Ser:
28
19
46
10
19
28
19
37
37
10
37
19
0
19
0
% S
% Thr:
10
0
10
0
19
0
0
0
0
0
10
19
10
37
10
% T
% Val:
0
0
0
28
0
0
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _